DUOPA IS DIFFERENT
Duopa is different since it delivers levodopa continuously over 16 hours. This can help you get back more time in your day.
*In a clinical trial, 71 advanced Parkinson’s patients with persistent “off” time, despite taking Parkinson’s medications (including carbidopa/levodopa pills), took either Duopa or carbidopa/levodopa immediate-release (IR) pills for 12 weeks. The change in average daily “off” time from study start to Week 12 was measured over 16-hour days during which patients were awake. At study beginning, average daily “off” time: 6.3 hours in Duopa group, 6.9 hours in carbidopa/levodopa IR pill group.
FREES YOU FROM SO MANY LEVODOPA PILLS
†Patients remained on other Parkinson’s medications and could take carbidopa/levodopa IR pills as needed for nighttime or rescue.
‡Based on average oral levodopa dose (25-mg carbidopa/100-mg levodopa).
Your doctor will individualize your Duopa dose to meet your needs – and may adjust your other Parkinson’s medications, too.
Think about how often you take levodopa pills. What if you had fewer interruptions in your day?
Stomach or intestine problems and problems from the procedure you will need to have to receive DUOPA may occur; some of these may require surgery and may lead to death.
Serious side effects may include: a blockage of your stomach or intestines (bezoar); stopping movement through intestines (ileus); drainage, redness, swelling, pain, feeling of warmth around the small hole in your stomach wall (stoma); bleeding from stomach ulcers or your intestines; inflammation of your pancreas (pancreatitis); infection in your lungs (pneumonia); air or gas in your abdominal cavity; skin infection around the intestinal tube, pocket of infection (abscess), or infection in your blood (sepsis) or abdominal cavity may occur after surgery; stomach pain, nausea, or vomiting.
The most common side effects of DUOPA include: complications of tubing placement procedure, swelling of legs and feet, nausea, high blood pressure (hypertension), depression, and mouth and throat pain.
WHAT DO REAL PATIENTS THINK?
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DUOPA (carbidopa and levodopa) enteral suspension is a prescription medicine used for treatment of advanced Parkinson’s disease. DUOPA contains two medicines: carbidopa and levodopa.
What is the most important safety information I should know about DUOPA?
Your healthcare provider will talk to you about the stoma procedure. Before the stoma procedure, tell your healthcare provider if you ever had a surgery or problems with your stomach.
Talk to your healthcare provider about what you need to do to care for your stoma. After the procedure, you and your healthcare provider will need to regularly check the stoma for any signs of infection.
Do not take DUOPA if you currently take or have recently taken (within 2 weeks) a medication for depression called a non-selective monoamine oxidase (MAO) inhibitor. Ask your healthcare provider or pharmacist if you are not sure if you take an MAO inhibitor.
Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Using DUOPA with certain other medicines, including medications for high blood pressure, MAO inhibitors, antipsychotics, metoclopramide, isoniazid, and iron or vitamin supplements, may cause serious side effects. High-protein foods may affect how DUOPA works. Tell your healthcare provider if you change your diet.
DUOPA may cause serious side effects. Talk to your doctor before starting DUOPA and while on DUOPA if you have had or have any of these:
Do not stop using DUOPA or change your dose unless you are told to do so by your healthcare provider. Tell your healthcare provider if you develop withdrawal symptoms such as fever, confusion, or severe muscle stiffness.
The most common side effects of DUOPA include: complications of tubing placement procedure, swelling of legs and feet, nausea, high blood pressure (hypertension), depression, and mouth and throat pain.
Please see the full Prescribing Information including Medication Guide for additional information about DUOPA. Talk to your healthcare provider if you have questions.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
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